Original Research Open access Published: 25 Jan 2026

Molecular Mechanisms of Filamentous Hemagglutinin- Mediated Suppression of IL-17 Signaling During Bordetella Infection

Michael Henderson, Carol Inatsuka, Amanda J. Sheets, Corinne L. Williams, David J. Benaron, Gina M. Donato, Mary C. Gray, Erik L. Hewlett, Peggy A. Cotter

  • Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, USA.
  • Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, USA.
  • Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, USA
Received 16 Oct 2025 Revised 7 Jan 2026 Accepted 21 Jan 2026 Published 25 Jan 2026 License CC BY 4.0

Keywords: Bordetella infection; filamentous hemagglutinin; IL-17 signaling; immune evasion; Th17 immune response

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Henderson, M., Inatsuka, C., Sheets, A. J. et al. Molecular Mechanisms of Filamentous Hemagglutinin- Mediated Suppression of IL-17 Signaling During Bordetella Infection. J. Exp. Integr. Med. 14, 6–10 (2026). https://www.jeim.org/articles/2614102